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The JWH molecules ended up very first synthesized by John William Huffman at Clemson University while in the late 1990s.[83] The FBI concluded inside of a 2012 memo that due to the publication of J.W. Huffman's investigate, people trying to find a "marijuana-like-high" would stick to his recipes and techniques.[5] PB-22 and 5F-PB-22 have been the